Di Carlo Microfluidics
UCLA Di Carlo
Publications
Peer Reviewed Journal Articles

47.   Dudani JS, Gossett DR, Tse HTK, Di Carlo D. Pinched-flow hydrodynamic stretching of single-cells. Lab on a Chip (2013). doi:10.1039/C3LC50649E
Link to article. HOT article highlight.

46.   Amini H, Sollier E, Masaeli M, Xie Y, Ganapathysubramanian B, Stone HA, and Di Carlo D. Engineering fluid flow using sequenced microstructures. Nature Communications (2013). doi:10.1038/ncomms2841
Link to article. PDF Download. R&D News. Process Engineering. Lab on a Chip Research Highlight.

45.  Chung AJ, Pulido D, Oka JC, Masaeli M, Amini H, and Di Carlo, D. Microstructure induced local helical vortices allow single-stream and long-term inertial focusing. Lab on a Chip (2013). doi:10.1039/C3LC41227J.
Link to article. Video 1, 2, 3.

44.  Mach AJ, Adeyiga O, Di Carlo D. Review: Microfluidic sample preparation for diagnostic cytopathology. Lab on a Chip (2013). doi:10.1039/C2LC41104K.
Link to article.

43.  Chung AJ, Gossett DR, Di Carlo D. Three dimensional, sheathless, and
high-throughput microparticle inertial focusing through geometry-induced
secondary flows. Small (2012). doi:10.1002/smll.201202413.
Link to article. Video 1, 2, 3, 4
Chung Di Carlo
42. Tseng, P, Judy JW, Di Carlo D. Magnetic nanoparticle-mediated massively parallel mechanical modulation of single-cell behavior. Nature Methods (2012). 
doi:10.1038/nmeth.2210.
Link to article.Video 1, 2, 3, 4, 5.
Tseng Di Carlo

41. Murray C, McCoul D, Sollier E, Ruggiero T, Niu X, Pei Q, Di Carlo D. Electro-adaptive microfluidics for active tuning of channel geometry using polymer actuators. Microfluidics and Nanofluidics (2012).
doi:10.1007/s10404012-1055-y. Link to article.

Murray Di Carlo

40. Hur SC, Brinckerhoff TZ, Walthers CM, Dunn JCY, Di Carlo D. Label-free enrichment of adrenal cortical progenitor cells using intertial microfluidics.
PLoS ONE (2012) 7(10): e46550. doi:10.1371/journal.pone.0046550.
Link to article.

39. Masaeli M, Sollier E, Amini H, Mao W, Camacho K, Doshi N, Mitragotri, S, Alexeev A, Di Carlo D. Continuous inertial focusing and separation of particles by shape. Physical Review X (2012) 2(3): 031017. doi:10.1103/PhysRevX.2.071017.
Link to article.
Research Highlights.Video
Masaeli Sollier Di Carlo

38. Weaver WM, Milisavljevic V, Miller JF, Di Carlo D. Fluid flow induces biofilm formation in Staphylococcus epidermidis polysaccharide intracellular adhesin-positive clinical isolates. Applied and Environmental Microbiology (2012) 78(16): 5890-5896. doi:10.1128/AEM.01139-12.
Link to article.

Amini Di Carlo

37. Amini H, Sollier E, Weaver WM, Di Carlo D. Intrinsic particle-induced lateral transport in microchannels. PNAS (2012) doi:10.1073/pnas.1207550109.
Link to article, LOC Research Highlight, UCLA News SciGuru. Video 1, 2, 3, 4, 5

Amini Di Carlo

36. Gossett DR, Tse HTK, Dudani JS, Goda K, Woods TA, Graves SW,
Di Carlo D. Inertial manipulation and transfer of microparticles across laminar fluid streams. Small (2012) doi:10.1002/smll.201200588. Link to article.

Gossett Di Carlo

35. Goda K, Ayazi A, Gossett DR, Sadasivam J, Lonappan CK, Sollier E,
Fard AM, Hur SC, Adam J, Murray C, Wang C, Brackbill N, Di Carlo D, Jalali B. High-throughput single-microparticle imaging flow analyzer. PNAS (2012) doi:10.1073/pnas.1204718109. Link to article
, PNAS Research Highlight, UCLA News
Goda Di Carlo

34. Tse HTK, Weaver WM, Di Carlo D. Increased asymmetric and multi-daughter cell division in mechanically confined microenvironments. PLoS ONE (2012) 7(6): e38986. doi:10.1371/journal.pone.0038986 Link to article, UCLA News, Real Clear Science Research Highlight, Real Clear Science Journal Club, Biology.About.com , Softpedia. Video 1, 2, 3, 4, 5, 6
Tse Weaver Di Carlo

33. Gossett DR, Tse HTK, Lee SA, Ying Y, Lindgren AG, Yang OO, Rao J,
Clark AT, Di Carlo D. Hydrodynamic stretching of single cells for large population mechanical phenotyping. PNAS (2012)
doi: 10.1073/pnas.1200107109.
Link to article, UCLA News, Nature Research Highlights, MedGadget, LOC Research Highlights.
Videos on Youtube Channel.
Gossett Tse Di Carlo

32. Di Carlo D. A Mechanical Biomarker of Cell State in Medicine.
Journal of Laboratory Automation
(2012) 17:1,
doi: 10.1177/2211068211431630.
Link to article.
Di Carlo

31. Tse HTK, Meng P, Gossett DR, Irturk A, Kastner R, Di Carlo D. Strategies for Implementing Hardware-Assisted High-Throughput Cellular Image Analysis.
Journal of Laboratory Automation
(2011) 16:6, (422-430); doi:10.1016/j.jala.2011.08.001.
Link to article. PDF.
Tse Di Carlo

30. Sollier E, Murray C, Maoddi P, Di Carlo D. Rapid Prototypng polymers for microfluidic devices and high pressure injections.
Lab on a Chip
(2011); doi: 10.1039/C1LC20514E.
Link to article.
 SC Hur Dino Di Carlo

29. Mach AJ, Kim JH, Arshi A, Hur SC, Di Carlo D. Automated cellular sample preparation using a Centrifuge-on-a-Chip.
Lab on a Chip
 (2011); doi:10.1039/c1lc20330d.

Paper selected for cover page article -
Link to article. Videos on Youtube Channel
Paper selected as HOT article in Lab on a Chip Blog. Link to Press medGadget, ideaConnection.

28. Hur SC, Choi SE, Kwon S, Di Carlo D. Inertial focusing of non-spherical microparticles.
Applied Physics Letters
 99, 044101 (2011); doi:10.1063/1.3608115 .
Link to article. Videos on Youtube Channel.
 SC Hur Dino Di Carlo

27. Hur SC, Mach AJ, Di Carlo D. High-throughput size-based rare cell enrichment using microscale vortices.
Biomicrofluidics
 5, 022206 (2011); doi:10.1063/1.3576780 .
Link to article. Featured in  Virtual Journal of Biological Physics Research vol 22 issue 1. Videos on Youtube Channel
 SC Hur Dino Di Carlo

26. Hur SC, Henderson-MacLennan NK, McCabe ERB, Di Carlo D. Deformability-based cell classification and enrichment using inertial microfluidics.
Lab on a Chip
2011; 10.1039/C0LC00595A.
Link to article. Research highlights in Lab on a Chip. Videos on Youtube Channel
Di Carlo Hur

25. Weaver WM, Dharmaraja S, Milisavljevic V, Di Carlo D. The Effects of Shear Stress on Isolated Receptor–ligand Interactions of Staphylococcus epidermidis and Human Plasma Fibrinogen Using Molecularly Patterned Microfluidics.
Lab on a Chip
2011;
10.1039/C0LC00414F. Link to article.
Di Carlo Weaver

24. Gossett DR, Weaver WM, Ahmed NS, Di Carlo D. Sequential Array Cytometry: Multi-Parameter Imaging with a Single Fluorescent Channel.
Annals of Biomedical Engineering 2010;
DOI: 10.1007/s10439-010-0199-8 . Link to article.

23. Lee W, Amini H, Stone HA, Di Carlo D. Dynamic Self Assembly and Control of Microfluidic Particle Crystals.
PNAS
2010; 10.1073/pnas.1010297107.
Link to article. Link to press at Science Daily, UCLA Newsroom, PhysOrg, TCE. Videos on Youtube Channel, EurekalertWonhee Lee Dino Di Carlo

22. Mach AJ, Di Carlo D. Continuous Scalable Blood Filtration Device Using Inertial Microfluidics.
Biotechnology and Bioengineering
2010; DOI:10.1002/bit.22833.
Paper selected for cover page article -
Link to Article
Videos on Youtube Channel
Dino Di Carlo

21. Gossett DR, Weaver WM, Mach AJ, Hur SC, Tse HTK, Lee W,
Amini H, Di Carlo D. Review: Label-free Cell Separation and Sorting in Microfluidic Systems.
Analytical and Bioanalytical Chemistry
2010; DOI:10.1007/s00216-010-3721-9.
Link
Dino Di Carlo

20. Oakey J, Applegate RW, Arellano E Jr, Di Carlo D, Graves SW, Toner M. Particle Focusing in Staged Inertial Microfluidic Devices for Flow Cytometry. Analytical Chemistry 2010; DOI:10.1021/ac100387b. Link
Dino Di Carlo

19. Heikali D, Di Carlo D. A Niche for Microfluidics in Portable Hematology Analyzers.
Journal of the Association for Laboratory Automation
2010; DOI:10.1016/j.jala.2010.02.005.
Link
Dino Di Carlo

18. Hur SC, Tse HTK, Di Carlo D. Sheathless inertial cell ordering for extreme throughput flow cytometry.
Lab on a Chip
2010; 10:274-280. (Selected for cover page article) Article Link Featured in Chemical Biology Highlights
Videos on Youtube Channel
Di Carlo Hur

17. Di Carlo D. Inertial Microfluidics Review Article.
Lab on a Chip 2009; 9:3038-3046.
Link

16. Gossett DR, Di Carlo D. Particle Focusing Mechanisms in Curving Confined Flows.
Analytical Chemistry 2009 81(20) 8459-8465.
Link Videos on Youtube Channel
Danny Gosset 2009

15.Tseng P, Di Carlo D, Judy JW. Rapid and Dynamic Intracellular Patterning of Cell-Internalized Magnetic Fluorescent Nanoparticles.
Nano Letters
2009; 9: 3053–3059.
Link

14. Russom A, Gupta AK, Nagrath S, Di Carlo D, Edd JF, Toner M. Differential Inertial Focusing of Particles in Curved Low-Aspect-Ratio Microchannels. New Journal of Physics 2009; 11: 075025. Link

Dino Di Carlo

13. Di Carlo D, Edd JF, Humphry KJ, Stone HA, Toner M. Particle Segregation and Dynamics in Confined Flows.
Physical Review Letters 2009; 102:094503.
Link

12. Hsu CH, Di Carlo D, Chen C, Irimia D, Toner M. Microvortex for Focusing, Guiding and Sorting of Particles.
Lab on a Chip 2008; 8:2128-34.
Link

11. Edd JF, Di Carlo D, Humphry KJ, Koester S, Irimia D, Weitz DA, Toner M. Controlled Encapsulation of Single-Cells into Monodisperse Picolitre Drops.
Lab on a Chip 2008; 8:1262-4.
Link

10. Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M. Equilibrium Separation and Filtration of Particles Using Differential Inertial Focusing.
Analytical Chemistry
2008; 80:2204-11.
Link

9. Di Carlo D, Irimia D, Tompkins RG, Toner M. Continuous Inertial Focusing, Ordering and Separation of Particles in Microchannels.
Proceedings of the National Academy of Sciences USA
2007;104:18892-18897. (Editor's Choice in Science)
Link

8. Wu LY, Di Carlo D, Lee LP. Microfluidic Self-Assembly of Tumor Spheroids for Anti-Cancer Drug Discovery.
Biomedical Microdevices
2007; 8:1387-2176.
Link

7. Di Carlo D, and Lee LP. Dynamic Single-Cell Analysis for Quantitative Biology. Analytical Chemistry 2006;78:7918-7925. (Selected as cover page article) Link
Dino Di Carlo Cell Trap

6. Di Carlo D, Aghdam N, Lee LP. Single-Cell Enzyme Concentrations, Kinetics, and Inhibition Analysis Using High-Density Hydrodynamic Cell Isolation Arrays. Analytical Chemistry 2006;78:4925 - 4930. (Highlighted in Analytical Chemistry) Link

5. Di Carlo D, Wu LY, Lee LP. Dynamic Single Cell Culture Array.
Lab on a Chip
2006; 6:1445-1449.
Link

4. Ionescu-Zanetti C, Nevill JT, Di Carlo D, Jeong KH, Lee LP. Nanogap capacitors: Sensitivity to sample permittivity changes.
Journal of Applied Physics
2006;99:Art. No. 024305.

3. Di Carlo D, Ionescu-Zanetti C, Zhang Y, Hung PJ, Lee LP. On-Chip Cell Lysis by Local Hydroxide Generation.
Lab on a Chip
2005;5:171-178. (Selected as a hot article)
Link

2. Ionescu-Zanetti C, Wang L, Di Carlo D, Hung P, Di Blas A, Hughey R, Lee LP. Alkaline Hemolysis Fragility is Dependent on Cell Shape: Results From a Morphology Tracker.
Cytometry Part A
2005;65A:116-123
Link
Di Carlo

1. Di Carlo D, Jeong K, Lee LP. Reagentless Mechanical Cell Lysis by Nanoscale Barbs in Microchannels for Sample Preparation.
Lab on a Chip 2003;3:287-291.(Selected as a hot article) Link