Inertial Focusing Designs II

[dicarloforums]

Brief description:
Inertial focusing microchannels of varying sizes that were used in studies to focus microparticles. A dilute solution of cells/particles is introduced into the inlet of the channel and flowed at high velocities to create well-focused particles streams at the outlet. Single-turn channels were also used to study particle focusing mechanisms in curving channels.

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Picture of some of the inertial focusing channel designs in the AutoCAD file.

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One second exposure fluorescent streak images of 10-um green fluorescent beads in various devices (left) and assembled streak images across a range of flow rates (right) to demonstrate how equilibrium positions depend on flow rate.


Conversion:
1 unit = 1 micrometer


Layers:
Layer 1 (cyan): channel layer
height: 50-60 um


References:
Particle Focusing Mechanisms in Curving Confined Flows
Daniel R. Gossett, Dino Di Carlo
Analytical Chemistry 2009 81 (20), 8459-8465